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Investigating the role of Hedgehog/GLI1 signaling in glioblastoma cell response to temozolomide
Resistance to chemotherapy substantially hinders successful glioblastoma (GBM) treatment, contributing to an almost 100% mortality rate. Resistance to the frontline chemotherapy, temozolomide (TMZ), arises from numerous signaling pathways that are deregulated in GBM, including Hedgehog (Hh) signalin...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007474/ https://ncbi.nlm.nih.gov/pubmed/29930746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25467 |
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