Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis

Haploid mouse embryonic stem cells (ESCs), in which a single hit mutation is sufficient to produce loss-of-function phenotypes, have provided a powerful tool for forward genetic screening. This strategy, however, can be hampered by undesired autodiploidization of haploid ESCs. To overcome this obsta...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Yamanishi, Ayako, Matsuba, Atsushi, Kondo, Ryohei, Akamatsu, Rie, Tanaka, Sachiyo, Tokunaga, Masahiro, Horie, Kyoji, Kokubu, Chikara, Ishida, Yasumasa, Takeda, Junji
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007410/
https://ncbi.nlm.nih.gov/pubmed/29554276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky183
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker