A Critical Role of Mitochondria in BDNF-Associated Synaptic Plasticity After One-Week Vortioxetine Treatment

BACKGROUND: Preclinical studies have indicated that antidepressant effect of vortioxetine involves increased synaptic plasticity and promotion of spine maturation. Mitochondria dysfunction may contribute to the pathophysiological basis of major depressive disorder. Taking into consideration that vor...

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Détails bibliographiques
Publié dans:Int J Neuropsychopharmacol
Auteurs principaux: Chen, Fenghua, Danladi, Jibrin, Ardalan, Maryam, Elfving, Betina, Müller, Heidi K, Wegener, Gregers, Sanchez, Connie, Nyengaard, Jens R
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Regular Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007239/
https://ncbi.nlm.nih.gov/pubmed/29514282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy022
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