A Critical Role of Mitochondria in BDNF-Associated Synaptic Plasticity After One-Week Vortioxetine Treatment

BACKGROUND: Preclinical studies have indicated that antidepressant effect of vortioxetine involves increased synaptic plasticity and promotion of spine maturation. Mitochondria dysfunction may contribute to the pathophysiological basis of major depressive disorder. Taking into consideration that vor...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Chen, Fenghua, Danladi, Jibrin, Ardalan, Maryam, Elfving, Betina, Müller, Heidi K, Wegener, Gregers, Sanchez, Connie, Nyengaard, Jens R
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Regular Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007239/
https://ncbi.nlm.nih.gov/pubmed/29514282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy022
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