A Critical Role of Mitochondria in BDNF-Associated Synaptic Plasticity After One-Week Vortioxetine Treatment

BACKGROUND: Preclinical studies have indicated that antidepressant effect of vortioxetine involves increased synaptic plasticity and promotion of spine maturation. Mitochondria dysfunction may contribute to the pathophysiological basis of major depressive disorder. Taking into consideration that vor...

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Dettagli Bibliografici
Pubblicato in:Int J Neuropsychopharmacol
Autori principali: Chen, Fenghua, Danladi, Jibrin, Ardalan, Maryam, Elfving, Betina, Müller, Heidi K, Wegener, Gregers, Sanchez, Connie, Nyengaard, Jens R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Regular Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007239/
https://ncbi.nlm.nih.gov/pubmed/29514282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy022
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