A Critical Role of Mitochondria in BDNF-Associated Synaptic Plasticity After One-Week Vortioxetine Treatment

BACKGROUND: Preclinical studies have indicated that antidepressant effect of vortioxetine involves increased synaptic plasticity and promotion of spine maturation. Mitochondria dysfunction may contribute to the pathophysiological basis of major depressive disorder. Taking into consideration that vor...

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Vydáno v:Int J Neuropsychopharmacol
Hlavní autoři: Chen, Fenghua, Danladi, Jibrin, Ardalan, Maryam, Elfving, Betina, Müller, Heidi K, Wegener, Gregers, Sanchez, Connie, Nyengaard, Jens R
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Regular Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007239/
https://ncbi.nlm.nih.gov/pubmed/29514282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy022
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