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A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1

It is now established that cholesterol oxidation products (oxysterols) are involved in several events underlying Alzheimer's disease (AD) pathogenesis. Of note, certain oxysterols cause neuron dysfunction and degeneration but, recently, some of them have been shown also to have neuroprotective...

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Publicado en:Redox Biol
Autores principales: Testa, Gabriella, Staurenghi, Erica, Giannelli, Serena, Gargiulo, Simona, Guglielmotto, Michela, Tabaton, Massimo, Tamagno, Elena, Gamba, Paola, Leonarduzzi, Gabriella
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007083/
https://ncbi.nlm.nih.gov/pubmed/29883958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.05.009
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