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The Listeriolysin O PEST-like Sequence Co-opts AP-2-Mediated Endocytosis to Prevent Plasma Membrane Damage during Listeria Infection

Listeriolysin O (LLO) is a cholesterol-dependent cytolysin that mediates escape of Listeria monocytogenes from a phagosome, enabling growth of the bacteria in the host cell cytosol. LLO contains a PEST-like sequence that prevents it from killing infected cells, but the mechanism involved is unknown....

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Chen, Chen, Nguyen, Brittney N., Mitchell, Gabriel, Margolis, Shally R., Ma, Darren, Portnoy, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007032/
https://ncbi.nlm.nih.gov/pubmed/29902442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.05.006
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