Inducible Control of Virulence Gene Expression in Listeria monocytogenes: Temporal Requirement of Listeriolysin O during Intracellular Infection

We have constructed a lac repressor/operator-based system to tightly regulate expression of bacterial genes during intracellular infection by Listeria monocytogenes. An L. monocytogenes strain was constructed in which expression of listeriolysin O was placed under the inducible control of an isoprop...

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Autors principals: Dancz, Christina E., Haraga, Andrea, Portnoy, Daniel A., Higgins, Darren E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Molecular Biology of Pathogens
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135386/
https://ncbi.nlm.nih.gov/pubmed/12374827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.21.5935-5945.2002
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