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Numerical study of gene electrotransfer efficiency based on electroporation volume and electrophoretic movement of plasmid DNA

BACKGROUND: The efficiency of gene electrotransfer, an electroporation-based method for delivery of pDNA into target tissues, depends on several processes. The method relies on application of electric pulses with appropriate amplitude and pulse duration. A careful choice of electric pulse parameters...

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Publicat a:Biomed Eng Online
Autors principals: Forjanič, Tadeja, Miklavčič, Damijan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006849/
https://ncbi.nlm.nih.gov/pubmed/29914508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12938-018-0515-3
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