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Numerical optimization of gene electrotransfer into muscle tissue

BACKGROUND: Electroporation-based gene therapy and DNA vaccination are promising medical applications that depend on transfer of pDNA into target tissues with use of electric pulses. Gene electrotransfer efficiency depends on electrode configuration and electric pulse parameters, which determine the...

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Bibliografiske detaljer
Main Authors: Zupanic, Anze, Corovic, Selma, Miklavcic, Damijan, Pavlin, Mojca
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990758/
https://ncbi.nlm.nih.gov/pubmed/21050435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-9-66
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