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Numerical optimization of gene electrotransfer into muscle tissue

BACKGROUND: Electroporation-based gene therapy and DNA vaccination are promising medical applications that depend on transfer of pDNA into target tissues with use of electric pulses. Gene electrotransfer efficiency depends on electrode configuration and electric pulse parameters, which determine the...

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Main Authors: Zupanic, Anze, Corovic, Selma, Miklavcic, Damijan, Pavlin, Mojca
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990758/
https://ncbi.nlm.nih.gov/pubmed/21050435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-9-66
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