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Numerical optimization of gene electrotransfer into muscle tissue

BACKGROUND: Electroporation-based gene therapy and DNA vaccination are promising medical applications that depend on transfer of pDNA into target tissues with use of electric pulses. Gene electrotransfer efficiency depends on electrode configuration and electric pulse parameters, which determine the...

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Hlavní autoři: Zupanic, Anze, Corovic, Selma, Miklavcic, Damijan, Pavlin, Mojca
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990758/
https://ncbi.nlm.nih.gov/pubmed/21050435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-9-66
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