MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation

We show for the first time that, in contrast to other glutathione transferases and peroxidases, deletion of microsomal glutathione transferase 1 (MGST1) in mice is embryonic lethal. To elucidate why, we used zebrafish development as a model system and found that knockdown of MGST1 produced impaired...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Redox Biol
Autores principales: Bräutigam, Lars, Zhang, Jie, Dreij, Kristian, Spahiu, Linda, Holmgren, Arne, Abe, Hiroshi, Tew, Kenneth D., Townsend, Danyelle M., Kelner, Michael J., Morgenstern, Ralf, Johansson, Katarina
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006721/
https://ncbi.nlm.nih.gov/pubmed/29702404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.013
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares