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OCT4B regulates p53 and p16 pathway genes to prevent apoptosis of breast cancer cells

Octamer-binding transcription factor 4 (OCT4) is a transcription factor with a well-defined role in stem cell pluripotency. Two OCT4 isoforms, OCT4A and OCT4B, tend to be downregulated as normal cells differentiate. However, OCT4, particularly OCT4B, may become reactivated in cancer cells. Despite t...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Meng, Lu, Hu, Hongyu, Zhi, Huifang, Liu, Yue, Shi, Fangyu, Zhang, Laiguang, Zhou, Yanjun, Lin, Aixing
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006504/
https://ncbi.nlm.nih.gov/pubmed/29930717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8607
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