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OCT4B regulates p53 and p16 pathway genes to prevent apoptosis of breast cancer cells
Octamer-binding transcription factor 4 (OCT4) is a transcription factor with a well-defined role in stem cell pluripotency. Two OCT4 isoforms, OCT4A and OCT4B, tend to be downregulated as normal cells differentiate. However, OCT4, particularly OCT4B, may become reactivated in cancer cells. Despite t...
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| Publicado no: | Oncol Lett |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006504/ https://ncbi.nlm.nih.gov/pubmed/29930717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8607 |
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