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The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells

The aim of this study was to determine the anticancer potential of Leonurus sibiricus extract derived from in vitro transgenic roots transformed by Agrobacetrium rhizogenes with AtPAP1 transcriptional factor, and that of transformed roots without construct, on grade IV human glioma cells and the U87...

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Dades bibliogràfiques
Publicat a:Neurochem Res
Autors principals: Sitarek, Przemysław, Kowalczyk, Tomasz, Santangelo, Simona, Białas, Adam J., Toma, Monika, Wieczfinska, Joanna, Śliwiński, Tomasz, Skała, Ewa
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006195/
https://ncbi.nlm.nih.gov/pubmed/29786770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-018-2551-6
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