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The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells

The aim of this study was to determine the anticancer potential of Leonurus sibiricus extract derived from in vitro transgenic roots transformed by Agrobacetrium rhizogenes with AtPAP1 transcriptional factor, and that of transformed roots without construct, on grade IV human glioma cells and the U87...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Sitarek, Przemysław, Kowalczyk, Tomasz, Santangelo, Simona, Białas, Adam J., Toma, Monika, Wieczfinska, Joanna, Śliwiński, Tomasz, Skała, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006195/
https://ncbi.nlm.nih.gov/pubmed/29786770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-018-2551-6
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