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α7 Nicotinic receptor-modulating agents reverse the hyperdopaminergic tone in the MAM model of schizophrenia

Recent evidence has emerged supporting a role for the cholinergic system in schizophrenia, including the potential of α7 modulators as a treatment strategy. However, preclinical studies to date have relied on studies in normal systems rather than on a validated developmental model of schizophrenia....

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Publicat a:Neuropsychopharmacology
Autors principals: Neves, Gilda A, Grace, Anthony A
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006162/
https://ncbi.nlm.nih.gov/pubmed/29695783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0066-0
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