Загрузка...
Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy
BACKGROUND: Microsatellite instability-high (MSI-H) and polymerase ε (POLE)-mutated metastatic colorectal cancer (mCRC) represent hypermutated and ultramutated tumor phenotypes, respectively, that may predict benefit to checkpoint blockade [anti-programmed cell death 1 (PD-1)/programmed death ligand...
Сохранить в:
| Опубликовано в: : | J Gastrointest Oncol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
AME Publishing Company
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006042/ https://ncbi.nlm.nih.gov/pubmed/29998005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2018.01.09 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|