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(18)F-fluoromisonidazole predicts evofosfamide uptake in pancreatic tumor model
BACKGROUND: Quantitative imaging can facilitate patient stratification in clinical trials. The hypoxia-activated prodrug evofosfamide recently failed a phase III trial in pancreatic cancer. However, the study did not attempt to select for patients with hypoxic tumors. We tested the ability of (18)F-...
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| Publicado no: | EJNMMI Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005997/ https://ncbi.nlm.nih.gov/pubmed/29916085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0409-1 |
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