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Modeling the functions of condensin in chromosome shaping and segregation
The mechanistic details underlying the assembly of rod-shaped chromosomes during mitosis and how they segregate from each other to act as individually mobile units remain largely unknown. Here, we construct a coarse-grained physical model of chromosomal DNA and condensins, a class of large protein c...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005465/ https://ncbi.nlm.nih.gov/pubmed/29912867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006152 |
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