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Modeling the functions of condensin in chromosome shaping and segregation

The mechanistic details underlying the assembly of rod-shaped chromosomes during mitosis and how they segregate from each other to act as individually mobile units remain largely unknown. Here, we construct a coarse-grained physical model of chromosomal DNA and condensins, a class of large protein c...

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Publicat a:PLoS Comput Biol
Autors principals: Sakai, Yuji, Mochizuki, Atsushi, Kinoshita, Kazuhisa, Hirano, Tatsuya, Tachikawa, Masashi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005465/
https://ncbi.nlm.nih.gov/pubmed/29912867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006152
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