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A quest for clarity in bone erosion: The role of sequestosome 1 in Paget's disease of bone

Alterations in the SQSTM1 gene are a putative cause of Paget's disease of bone, yet results are conflicting about how these mutations impact osteoclasts, the cell type believed to be the main pathological contributor. In this issue of JBC, Zach et al. provide important new evidence that the pro...

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Pubblicato in:J Biol Chem
Autori principali: Michalski, Megan N., Williams, Bart O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005432/
https://ncbi.nlm.nih.gov/pubmed/29907733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.003689
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