Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling

Autosomal dominant polycystic kidney disease (ADPKD) is a debilitating disease that is characterized by the accumulation of numerous fluid-filled cysts in the kidney. ADPKD is primarily caused by mutations in two genes, PKD1 and PKD2. Long noncoding RNAs (lncRNA), defined by a length >200 nucleot...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Aboudehen, Karam, Farahani, Shayan, Kanchwala, Mohammed, Chan, Siu Chiu, Avdulov, Svetlana, Mickelson, Alan, Lee, Dayeon, Gearhart, Micah D., Patel, Vishal, Xing, Chao, Igarashi, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
RNA
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005429/
https://ncbi.nlm.nih.gov/pubmed/29716997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001723
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