A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding

Mmi1 is an essential RNA-binding protein in the fission yeast Schizosaccharomyces pombe that eliminates meiotic transcripts during normal vegetative growth. Mmi1 contains a YTH domain that binds specific RNA sequences, targeting mRNAs for degradation. The YTH domain of Mmi1 uses a noncanonical RNA-b...

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Vydáno v:J Biol Chem
Hlavní autoři: Stowell, James A. W., Wagstaff, Jane L., Hill, Chris H., Yu, Minmin, McLaughlin, Stephen H., Freund, Stefan M. V., Passmore, Lori A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005420/
https://ncbi.nlm.nih.gov/pubmed/29695507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002291
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