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Linking the YTH domain to cancer: the importance of YTH family proteins in epigenetics

N6-methyladenosine (m6A), the most prevalent and reversible modification of mRNA in mammalian cells, has recently been extensively studied in epigenetic regulation. YTH family proteins, whose YTH domain can recognize and bind m6A-containing RNA, are the main “readers” of m6A modification. YTH family...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Shi, Rongkai, Ying, Shilong, Li, Yadan, Zhu, Liyuan, Wang, Xian, Jin, Hongchuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016981/
https://ncbi.nlm.nih.gov/pubmed/33795663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03625-8
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