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Functional analysis of BARD1 missense variants in homology directed repair of DNA double strand breaks
Genes associated with hereditary breast and ovarian cancer (HBOC) are often sequenced in search of mutations that are predictive of susceptibility to these cancer types, but the sequence results are frequently ambiguous due to detection of missense substitutions for which the clinical impact is unkn...
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| Publicado no: | Hum Mutat |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005381/ https://ncbi.nlm.nih.gov/pubmed/26350354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22902 |
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