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Current understanding of reovirus oncolysis mechanisms
Mammalian orthoreovirus (reovirus) is under development as a cancer virotherapy. Clinical trials demonstrate that reovirus-based therapies are safe and tolerated in patients with a wide variety of cancers. Although reovirus monotherapy has proven largely ineffective, reovirus sensitizes cancer cells...
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| Veröffentlicht in: | Oncolytic Virother |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005300/ https://ncbi.nlm.nih.gov/pubmed/29942799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S143808 |
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