Genetic and Epigenetic Features of Rapidly Progressing IDH-Mutant Astrocytomas

IDH-mutant astrocytomas are significantly less aggressive than their IDH-wildtype counterparts. We analyzed The Cancer Genome Atlas dataset (TCGA) and identified a small group of IDH-mutant, WHO grade II–III astrocytomas (n = 14) with an unexpectedly poor prognosis characterized by a rapid progressi...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Richardson, Timothy E, Sathe, Adwait Amod, Kanchwala, Mohammed, Jia, Gaoxiang, Habib, Amyn A, Xiao, Guanghua, Snuderl, Matija, Xing, Chao, Hatanpaa, Kimmo J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005148/
https://ncbi.nlm.nih.gov/pubmed/29741737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nly026
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