The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis

BACKGROUND: Tuberculosis remains a huge public health problem and the prolonged treatment duration obstructs effective tuberculosis control. Higher rifampicin doses have been associated with better bactericidal activity, but optimal dosing is uncertain. This analysis aimed to characterize the relati...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Svensson, Elin M, Svensson, Robin J, te Brake, Lindsey H M, Boeree, Martin J, Heinrich, Norbert, Konsten, Sarah, Churchyard, Gavin, Dawson, Rodney, Diacon, Andreas H, Kibiki, Gibson S, Minja, Lilian T, Ntingiya, Nyanda E, Sanne, Ian, Gillespie, Stephen H, Hoelscher, Michael, Phillips, Patrick P J, Simonsson, Ulrika S H, Aarnoutse, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005123/
https://ncbi.nlm.nih.gov/pubmed/29917079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy026
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