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A Fresh Look at Huntingtin mRNA Processing in Huntington’s Disease
Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by a mutation that expands the polyglutamine (CAG) repeat in exon 1 of the huntingtin (HTT) gene. Wild-type HTT protein interacts with other proteins to protect cells against toxic stimuli, mediate vesicle transport and endo...
Gardado en:
| Publicado en: | J Huntingtons Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
IOS Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004895/ https://ncbi.nlm.nih.gov/pubmed/29865084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-180292 |
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