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Dabrafenib and trametinib in BRAFV600E mutated glioma

BRAFV600E mutations have been identified in a number of glioma subtypes, most frequently in pleomorphic xanthoastrocytoma, ganglioglioma, pilocytic astrocytoma, and epithelioid glioblastoma. Although the development of BRAF inhibitors has dramatically improved the clinical outcome for patients with...

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Dades bibliogràfiques
Publicat a:CNS Oncol
Autors principals: Brown, Nicholas F, Carter, Thomas, Kitchen, Neil, Mulholland, Paul
Format: Artigo
Idioma:Inglês
Publicat: Future Medicine Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004887/
https://ncbi.nlm.nih.gov/pubmed/28984141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns-2017-0006
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