Exosome-mediated gefitinib resistance in lung cancer HCC827 cells via delivery of miR-21

Acquired resistance to gefitinib remains a major challenge in cancer treatment. In the present study, the effect of exosomes on the transmission of gefitinib resistance from gefitinib-resistant HCC827 lung cancer cells (H827R) to their gefitinib-sensitive counterparts and the potential underlying me...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Jing, Changwen, Cao, Haixia, Qin, Xiaobing, Yu, Shaorong, Wu, Jianzhong, Wang, Zhuo, Ma, Rong, Feng, Jifeng
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004702/
https://ncbi.nlm.nih.gov/pubmed/29928355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8604
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