Cisplatin-resistant lung cancer cell–derived exosomes increase cisplatin resistance of recipient cells in exosomal miR-100–5p-dependent manner

Exosomes derived from lung cancer cells confer cisplatin (DDP) resistance to other cancer cells. However, the underlying mechanism is still unknown. A549 resistance to DDP (A549/DDP) was established. Microarray was used to analyze microRNA (miRNA) expression profiles of A549 cells, A549/DDP cells, A...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Qin, Xiaobing, Yu, Shaorong, Zhou, Leilei, Shi, Meiqi, Hu, Yong, Xu, Xiaoyue, Shen, Bo, Liu, Siwen, Yan, Dali, Feng, Jifeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439933/
https://ncbi.nlm.nih.gov/pubmed/28553110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S131516
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