Potent antitumor effect of combination therapy with sub-optimal doses of Akt inhibitors and pomalidomide plus dexamethasone in multiple myeloma

Afuresertib (AFU), a novel inhibitor of the serine/threonine kinase AKT, has clinical efficacy as a monotherapy against hematological malignancies and is expected to be used in combination with standard therapies for multiple myeloma (MM). To develop a more effective and less toxic combination of im...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Kinoshita, Shiori, Ri, Masaki, Kanamori, Takashi, Aoki, Sho, Yoshida, Takashi, Narita, Tomoko, Totani, Haruhito, Ito, Asahi, Kusumoto, Shigeru, Ishida, Takashi, Komatsu, Hirokazu, Iida, Shinsuke
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004690/
https://ncbi.nlm.nih.gov/pubmed/29928335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8501
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