Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits

Proteasome inhibitors (PI), mainly targeting the β5 subunit of the 20S proteasome, are widely used in the treatment of multiple myeloma (MM). However, PI resistance remains an unresolved problem in the therapy of relapsed and refractory MM. To develop a new PI that targets other proteasome subunits,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Yoshida, Takashi, Ri, Masaki, Kanamori, Takashi, Aoki, Sho, Ashour, Reham, Kinoshita, Shiori, Narita, Tomoko, Totani, Haruhito, Masaki, Ayako, Ito, Asahi, Kusumoto, Shigeru, Ishida, Takashi, Komatsu, Hirokazu, Kitahata, Shun, Chiba, Takuya, Ichikawa, Satoshi, Iida, Shinsuke
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839415/
https://ncbi.nlm.nih.gov/pubmed/29515784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24160
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker