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Trajectories of cell-cycle progression from fixed cell populations

An accurate dissection of sources of cell-to-cell variability is crucial for quantitative biology at the single-cell level but has been challenging for the cell cycle. We present Cycler, a robust method that constructs a continuous trajectory of cell-cycle progression from images of fixed cells. Cyc...

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Pubblicato in:Nat Methods
Autori principali: Gut, Gabriele, Tadmor, Michelle D, Pe’er, Dana, Pelkmans, Lucas, Liberali, Prisca
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004611/
https://ncbi.nlm.nih.gov/pubmed/26301842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3545
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