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Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling

Toll-like receptor 4 interactor with leucine-rich repeats (Tril) functions as a coreceptor for Toll-like receptors (Tlrs) to mediate innate immune responses in adults. In embryos, Tril signals to promote degradation of the Bmp inhibitor, Smad7, to allow for blood formation. It is not known whether t...

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Publicado en:Mol Biol Cell
Main Authors: Kim, Hyung-Seok, McKnite, Autumn, Xie, Yuanyuan, Christian, Jan L.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004582/
https://ncbi.nlm.nih.gov/pubmed/29298840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0446
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