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Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors

BACKGROUND: Toll-like receptors (TLRs) play a central role in innate immunity. TLRs are membrane glycoproteins and contain leucine rich repeat (LRR) motif in the ectodomain. TLRs recognize and respond to molecules such as lipopolysaccharide, peptidoglycan, flagellin, and RNA from bacteria or viruses...

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Bibliografiske detaljer
Main Authors: Matsushima, Norio, Tanaka, Takanori, Enkhbayar, Purevjav, Mikami, Tomoko, Taga, Masae, Yamada, Keiko, Kuroki, Yoshio
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899181/
https://ncbi.nlm.nih.gov/pubmed/17517123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-124
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