Comparative Geometrical Analysis of Leucine-Rich Repeat Structures in the Nod-Like and Toll-Like Receptors in Vertebrate Innate Immunity

The NOD-like receptors (NLRs) and Toll-like receptors (TLRs) are pattern recognition receptors that are involved in the innate, pathogen pattern recognition system. The TLR and NLR receptors contain leucine-rich repeats (LRRs) that are responsible for ligand interactions. In LRRs short β-strands sta...

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Publicado en:Biomolecules
Autores principales: Matsushima, Norio, Miyashita, Hiroki, Enkhbayar, Purevjav, Kretsinger, Robert H.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598782/
https://ncbi.nlm.nih.gov/pubmed/26295267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031955
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