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PICK1 is essential for insulin production and the maintenance of glucose homeostasis

Protein interacting with C-kinase 1 (PICK1) is a peripheral membrane protein that controls insulin granule formation, trafficking, and maturation in INS-1E cells. However, global Pick1-knockout mice showed only a subtle diabetes-like phenotype. This raises the possibility that compensatory effects f...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Li, Jia, Mao, Zhuo, Huang, Jiandong, Xia, Jun
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004578/
https://ncbi.nlm.nih.gov/pubmed/29298842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-03-0204
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