A carregar...

Strategy for Extending Half-life in Drug Design and Its Significance

[Image: see text] Preclinical optimization of compounds toward viable drug candidates requires an integrated understanding of properties that impact predictions of the clinically efficacious dose. The importance of optimizing half-life, unbound clearance, and potency and how they impact dose predict...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Gunaydin, Hakan, Altman, Michael D., Ellis, J. Michael, Fuller, Peter, Johnson, Scott A., Lahue, Brian, Lapointe, Blair
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004573/
https://ncbi.nlm.nih.gov/pubmed/29937977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00018
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!