Overexpression of the Ubiquilin-4 (UBQLN4) is Associated with Cell Cycle Arrest and Apoptosis in Human Normal Gastric Epithelial Cell Lines GES-1 Cells by Activation of the ERK Signaling Pathway

BACKGROUND: Ubiquilin-4 (UBQLN4) is a component of the ubiquitin-proteasome system and regulates the degradation of many proteins implicated in pathological conditions. The aim of this study was to determine the role of UBQLN4 in regulating the proliferation and survival of the normal gastric epithe...

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Bibliographische Detailangaben
Veröffentlicht in:Med Sci Monit
Hauptverfasser: Huang, Shengkai, Dong, Xin, Wang, Jia, Ding, Jie, Li, Yan, Li, Dongdong, Lin, Hong, Wang, Wenjie, Zhao, Mei, Chang, Qing, Zhou, Ning, Cui, Wei, Huang, Changzhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2018
Schlagworte:
Lab/In Vitro Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004079/
https://ncbi.nlm.nih.gov/pubmed/29807370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.909621
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