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Telomerase can't handle the stress
Telomerase counteracts the telomere shortening that occurs with each round of cell division. In normal human cells, telomerase is repressed, leading to telomere shortening that triggers replicative senescence. However, in most tumors, telomerase is up-regulated and is essential for telomere maintena...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Genes Dev |
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| Κύριος συγγραφέας: | |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cold Spring Harbor Laboratory Press
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004074/ https://ncbi.nlm.nih.gov/pubmed/29802121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.316042.118 |
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