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A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs

Circular RNAs (circRNAs) are generated from many protein-coding genes. Most accumulate in the cytoplasm, but how circRNA localization or nuclear export is controlled remains unclear. Using RNAi screening, we found that depletion of the Drosophila DExH/D-box helicase Hel25E results in nuclear accumul...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Huang, Chuan, Liang, Dongming, Tatomer, Deirdre C., Wilusz, Jeremy E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004072/
https://ncbi.nlm.nih.gov/pubmed/29773557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.314856.118
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