Efficient RNA drug delivery using red blood cell extracellular vesicles

Most of the current methods for programmable RNA drug therapies are unsuitable for the clinic due to low uptake efficiency and high cytotoxicity. Extracellular vesicles (EVs) could solve these problems because they represent a natural mode of intercellular communication. However, current cellular so...

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Vydáno v:Nat Commun
Hlavní autoři: Usman, Waqas Muhammad, Pham, Tin Chanh, Kwok, Yuk Yan, Vu, Luyen Tien, Ma, Victor, Peng, Boya, Chan, Yuen San, Wei, Likun, Chin, Siew Mei, Azad, Ajijur, He, Alex Bai-Liang, Leung, Anskar Y. H., Yang, Mengsu, Shyh-Chang, Ng, Cho, William C., Shi, Jiahai, Le, Minh T. N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004015/
https://ncbi.nlm.nih.gov/pubmed/29907766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04791-8
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