Efficient RNA drug delivery using red blood cell extracellular vesicles

Most of the current methods for programmable RNA drug therapies are unsuitable for the clinic due to low uptake efficiency and high cytotoxicity. Extracellular vesicles (EVs) could solve these problems because they represent a natural mode of intercellular communication. However, current cellular so...

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Publicat a:Nat Commun
Autors principals: Usman, Waqas Muhammad, Pham, Tin Chanh, Kwok, Yuk Yan, Vu, Luyen Tien, Ma, Victor, Peng, Boya, Chan, Yuen San, Wei, Likun, Chin, Siew Mei, Azad, Ajijur, He, Alex Bai-Liang, Leung, Anskar Y. H., Yang, Mengsu, Shyh-Chang, Ng, Cho, William C., Shi, Jiahai, Le, Minh T. N.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004015/
https://ncbi.nlm.nih.gov/pubmed/29907766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04791-8
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