TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms

Primary cilia are sensory organelles that coordinate multiple cellular signaling pathways, including Hedgehog (HH), Wingless/Int (WNT) and Transforming Growth Factor-β (TGF-β) signaling. Similarly, primary cilia have been implicated in regulation of mTOR signaling, in which Tuberous Sclerosis Comple...

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Vydáno v:Cell Mol Life Sci
Hlavní autoři: Rosengren, Thomas, Larsen, Lasse Jonsgaard, Pedersen, Lotte Bang, Christensen, Søren Tvorup, Møller, Lisbeth Birk
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003990/
https://ncbi.nlm.nih.gov/pubmed/29396625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2761-8
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