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Modeling the blood-brain barrier: Beyond the endothelial cells

The blood-brain barrier (BBB) regulates the transport of ions, nutrients, and metabolites to help maintain proper brain function. This restrictive interface formed by brain microvascular endothelial cells excludes the majority of small and large molecule drugs from entering the brain, and blood-brai...

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Bibliografiske detaljer
Udgivet i:Curr Opin Biomed Eng
Main Authors: Gastfriend, Benjamin D., Palecek, Sean P., Shusta, Eric V.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003712/
https://ncbi.nlm.nih.gov/pubmed/29915815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobme.2017.11.002
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