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A selective class of inhibitors for the CLC-Ka chloride ion channel
CLC proteins are a ubiquitously expressed family of chloride-selective ion channels and transporters. A dearth of pharmacological tools for modulating CLC gating and ion conduction limits investigations aimed at understanding CLC structure/function and physiology. Herein, we describe the design, syn...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003504/ https://ncbi.nlm.nih.gov/pubmed/29669921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720584115 |
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