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Ca(2+)-activated Cl current predominates in threshold response of mouse olfactory receptor neurons

In mammalian olfactory transduction, odorants activate a cAMP-mediated signaling pathway that leads to the opening of cyclic nucleotide-gated (CNG), nonselective cation channels and depolarization. The Ca(2+) influx through open CNG channels triggers an inward current through Ca(2+)-activated Cl cha...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Li, Rong-Chang, Lin, Chih-Chun, Ren, Xiaozhi, Wu, Jingjing Sherry, Molday, Laurie L., Molday, Robert S., Yau, King-Wai
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003478/
https://ncbi.nlm.nih.gov/pubmed/29735665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803443115
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