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Cyclic-nucleotide–gated cation current and Ca(2+)-activated Cl current elicited by odorant in vertebrate olfactory receptor neurons

Olfactory transduction in vertebrate olfactory receptor neurons (ORNs) involves primarily a cAMP-signaling cascade that leads to the opening of cyclic-nucleotide–gated (CNG), nonselective cation channels. The consequent Ca(2+) influx triggers adaptation but also signal amplification, the latter by o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Rong-Chang, Ben-Chaim, Yair, Yau, King-Wai, Lin, Chih-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056050/
https://ncbi.nlm.nih.gov/pubmed/27647918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613891113
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