Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock

The N(6)-methylation of internal adenosines (m6A) in mRNA has been quantified and localized throughout the transcriptome. However, the physiological significance of m6A in most highly methylated mRNAs is unknown. It was demonstrated previously that the circadian clock, based on transcription-transla...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fustin, Jean-Michel, Kojima, Rika, Itoh, Kakeru, Chang, Hsin-Yi, Ye, Shiqi, Zhuang, Bowen, Oji, Asami, Gibo, Shingo, Narasimamurthy, Rajesh, Virshup, David, Kurosawa, Gen, Doi, Masao, Manabe, Ichiro, Ishihama, Yasushi, Ikawa, Masahito, Okamura, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003373/
https://ncbi.nlm.nih.gov/pubmed/29784786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721371115
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